不良研究所

Mountain Gorillas Have Herpes Virus Similar to That Found in Humans

Epstein Barr-Like Virus in Gorillas May Hold Clues for Conservation and Human Disease

Quick Summary

  • Mountain gorillas have their own version of Epstein-Barr virus
  • Though widespread, the virus carries little health risk for healthy mountain gorillas
  • Findings could advance understanding of human disease, while also helping gorillas

Scientists from the 不良研究所, have detected a herpes virus in wild mountain gorillas that is very similar to the Epstein-Barr virus in humans, according to a .

Epstein-Barr virus, or EBV, infects more than 90 percent of the human population, typically without major health consequences or symptoms. It can be challenging, however, for people with HIV/AIDS and suppressed immune systems, leading to certain forms of cancer. The Epstein-Barr virus is also one of the major causes of mononucleosis, commonly called the 鈥渒issing disease.鈥

The study found that the mountain gorillas, a critically endangered species, have their own version of this herpes virus 鈥 a specific strain of lymphocryptovirus 1, or GbbLCV-1. 

Virus widespread, but few symptoms

mountain gorilla chews plants
Collecting plants chewed by wild mountain gorillas can tell researchers a lot about the endangered species鈥 health. Photo courtesy Tierra Smiley Evans/不良研究所

For the study, 不良研究所 researchers from Gorilla Doctors collected plants chewed by wild mountain gorillas in Rwanda and Uganda and analyzed the saliva left on the plants. This noninvasive, oral sampling technique showed that the virus is widespread, infecting 52 percent of infant gorillas studied. That is a similar rate to what is found in human infants in less developed countries.

The researchers say that the virus carries little health risk for otherwise healthy mountain gorillas and, like EBV, is typically dormant in their bodies. None of the live gorillas studied showed symptoms of having it.

However, the research team found that some infant gorillas who died of natural causes and were necropsied had 鈥減ulmonary reactive lymphoid hyperplasia,鈥 a condition seen in human infants and young children with HIV/AIDS who become infected with EBV.

The findings could provide valuable information for human disease and have conservation implications for the gorillas.

鈥淰iruses can behave similarly in different species,鈥 said lead author Tierra Smiley Evans, a postdoctoral researcher with the 不良研究所 One Health Institute in the School of Veterinary Medicine. 鈥淟earning about how gorillas react to this virus in their natural setting may help us have a better understanding of how Epstein-Barr virus affects human infants.鈥

Mountain gorillas are one of humans鈥 closest genetic relatives. Among the great apes, they are among the most studied. Veterinarians from the , a partnership between the 不良研究所 Wildlife Health Institute and the nonprofit Mountain Gorilla Veterinary Project, treat injured wild mountain gorillas and can continue to study this condition in the future.

Additional co-authoring institutions include the 不良研究所 Center for Comparative Medicine, One Health Approach for Conservation 鈥 Gorilla Health Rwanda, and the Rwanda Development Board in Kigali, Rwanda.

The study was funded by a William J. Fulbright Fellowship and the USAID Emerging Pandemic Threats PREDICT project.  

Media Resources

Tierra Smiley Evans, 不良研究所 One Health Institute, (916) 952-0275, tsmevans@ucdavis.edu

Kat Kerlin, 不良研究所 News and Media Relations, 530-750-9195, kekerlin@ucdavis.edu

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